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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c304c5d7a4f13706ad5d24d0758695b969fed5fc5de024994a6ab21ddcad2188' 
  AND token = '5VXsZsN6naAif6qeM7NKz6GLb1YcrK1bppjoAAowZxg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}