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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9a9799ef08dec6c23227b3c48d8f54936e4c4c3031b2c6160962605672975831' 
  AND token = 'yi5FXuDoOHsUGP3oLSDmIDFDVcXLZjTyj+GFvO0zBoU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}