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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a3faa45f319a6c29ab0eedd09f673d063f9cd5452896362b90e83e07545378be' 
  AND token = '/EFeZQr/+aaxhgk8AMQR372FUGT0OOx5gS2lGoeFUCo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}