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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3d06541a3429f4dc5357fad2660b9b479b9d903e08e4045df80514bdcf43f121' 
  AND token = 'dnR7Bcpc3tMYd5JK7OXrDUtMtbUyIhUqCpm0MNpTaEw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}