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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f1eb718af57f2fdac6b267307c50deea2e09b88373eb09f400d39b7e81327ab5' 
  AND token = '5IEFGl2H+DTtxmsQKawHDQf8mY5rULa5y3BYGqJ4NFM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}