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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '665f8a8201612f4252a87e85871b0e1162933c61b53fc15b0492ded39de3512b' 
  AND token = 'iBssL1OCBBUD5GFWXRDNjfmgzx4SolQEcWW/UDGV2bE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}