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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a22a8a91be96f7c6438e0b91f4ce46185cbe114e05e8178083c5b15e69702432' 
  AND token = 'X6TccUSYfwEDtnlyBGw9fsIInq59F2GUq8Sw9yeIwe4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00054

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}