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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '91d4fac71e630e411d3bd0ec2292e46d25cdbae848265cc4181551b681418e0f' 
  AND token = 'BVY7LAYkwUMepOUP/3mFvCFcWN72DUPDRozKRTIFIiE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}