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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '45b119ed685c17817a4f1f3fec4c6e692a040eca45d736323ce3564d9b53f51c' 
  AND token = 'RU6kghrmmOm/Cky2eKFBYGpM84RFy05g171olSIS3d0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}