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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a30739a496d9212c99b95dc4db4d7992c978573fcfc6361cbd30d6a8d4b728b8' 
  AND token = 'LV4VisVp44H4o/u1oFth3+OhOg74wlpKMx4VAjgwuFk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}