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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3b05cd227ea9611460654dc0b11e4034e9ed77e6f8be6ab6d2150e7aa77830b2' 
  AND token = 'T/1ccVGUc92i+qZtMmFtIpiaDtPkC7hz4X9aZDgbTeY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}