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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'de42e90150a62720ce307abf29921e8ceef8f089bdd6d77d725d51df391b1a33' 
  AND token = 'I1zWkBaJkHXDUK7kRK8fg+zBBvrbR/rRiE5fQvm/dbc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}