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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '499cb8734ef7da2951cfb19164057235d9732d813da8bcb622154a226ce3239d' 
  AND token = 'iU8l+z72X3WapjrbhB9FCZw/yNSFOTlNd9H25MCtPb8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}