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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f7c2956f469e7c137c538814484a6f662ec252faece76a2ec1f4b516f2632304' 
  AND token = 'AYW90behhniEGZOTZgDN3vUMSaZTf8+MxiQdp82FTLU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}