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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '497bc91ace70247b52bf6b67a1d8020d0c3233bd958f65731f32fcf38a5fc163' 
  AND token = 'vEi4pv53c/0ButFfLtwmDr+6/7QfDfLeCgdNUPY72PY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}