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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd1e252dd5cf5b618e839e71e8786b157caf817269c64c4804274b575c3962dd8' 
  AND token = '1ph/hxMNq/aw7x6/G2JTp4acPAuq7YMl1DSt3abYfc0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}