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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bff08c0cb2cf15a4b11a5471c94faef14a2230fd749381515264c27b1425f7e6' 
  AND token = 'uTIjP2xhvyX8Cu1lhqx24W3+mMpGZkDkveiiuaP0DJg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}