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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '76e33a1da362a16844725009bf7b3e3af4c27e81f5fe1d3e23fe5946a5364e41' 
  AND token = 'xf1sIxicwLrtKFXpHOzTlyulFGmRNGngbTLDsZzMaNw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}