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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b349065b8d4df563fc694cbe07e8c1b545a27558f65336cbb6a5499d3a1c6a12' 
  AND token = 'Vx2vSPIgPukJ/dVGe+bdWTMsEPpXAH/XGMFdVL3fWnE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}