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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3bc197f0490933531b2e3e5ed303d7c62e81d9e45b24321e5f5f16825e1e0617' 
  AND token = 'Zw8iPOwKrMpFvLiAqw93so4obngbspWOQpnqECCAKIQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}