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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bd159d6677a2271203098f44f6142682fdc9403101facfbc02f64f69a960abec' 
  AND token = 'yk5YOVUGsxhp6fyE2vwLnmkt4YNpmmAlJ9Edof+c2n8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}