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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '053c276e2ecb309258b673ebab62fdc02ff8c8aa1184fe1a1ac56f5d95e5b06d' 
  AND token = 'CANc0cC/togQInrseAEcOuqCX4s02C44ycHGcekIlHw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00052

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}