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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '175226f4312d326feee8c201cf9265bc302c4280178e9d40fc6a7bf44629ac28' 
  AND token = 'ngQOMESl7VGFkN02hVvyBf7gHB5JfWrF2UHv9bCB0fo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}