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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0743c0874805708a7111b83f386aba62de892d1ae51316d4b3d990f33b986218' 
  AND token = 'ozT9yP6QDTOgkzT6YdNQR35rGIg6hufuh99fZEd6tSk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}