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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e220039f6459387f8e9ccbdea87bf9906b2d7ca6aad2c5a806a68539c16010b6' 
  AND token = 'GokDRXaBQmgHiRhxJx3XO+723cv2IoS/bB1wO8FT44k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}