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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7488cc8c14c07780362eda75aed1dc209749b26c4dea25a41c1841fbebdd5809' 
  AND token = 'COg3yf/7IiCL0i4pjP0nI5RAJ8OCt7W3RzqD+1ZL68o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}