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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7f22cf02a7d6bc6db0f2d1543923cd1cf3dc074b366e1dc1647c86f6af1cd501' 
  AND token = '2ZX/bcsIZ3g25NY5MSdoVJxEGnBxlTVRf9nUvuerv0g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}