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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7b537afe2a0961000b90dd0dd2ee7c384374f88c72ab82d4588bd737e85e616e' 
  AND token = '0ZS38fgRqKYeE81XzE20tM2quilOBFEv+HSpMfApZbw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}