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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '50f7318fd9b108c5cfaa0f35358e63e1519105d4e5992f212e30ec84e4e20784' 
  AND token = 'c2WoYQQpuOcVkjrUvXEfROW7YlWXEstIHiYngYBbZTc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}