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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'aa080f20ae52015ae4274d35eaa69103fbb78a479f06dced0438a54a9dee93e7' 
  AND token = 'DwVI6lyC88Mv4JgJfLbeoEnQiWl9A2Zz3UZh8Zx8NhI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}