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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e12cae55e04b857238df88dd3dddffc9a4e4973ff4bb4b223a9ae214f2ac81c1' 
  AND token = 'xt4c5c85NpRIkg8u1+T0Uw+4Vu5yvJAUycZ9nFxmN+8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}