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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '506653d4a5221f58457bbf7d569bfd7c54e77b0a5d93a04ce462919cba129d1f' 
  AND token = 'VgTkJ1DP2wINHufgNY3+HlIUh0OK+u4EEG8I+5KSuA4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}