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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '72ad40b1c29594058197acd4cdc6016540886f8fe8f85f99506c0f38cfb2f455' 
  AND token = '1RSSTahrSxHm3vhqFOwcWgcw5+OX4F92ZDdrE8BPaZw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}