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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '53839184c5c1a2ea7eb860504259625b4ecb4fad01344febdfd8e0c4fbf45762' 
  AND token = 'dmlWZo0XPt5U/X4PQQcDOWPIPqYiu0Us6+urvU0aeLQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}