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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '663e8e57da02e29fa738bdeec18ec779d5b91dcafe0a78f1a1316158a8660348' 
  AND token = 'oU7883bV9Hp2jRQ6sVkrshCs0Hva6dC5hOHQ6MNAj3I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}