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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ff1154199475f9a34e33480f5f824cba8f95e80ea3dc0fb7e772201055374d8f' 
  AND token = 'nDxN6FeqKUpE9pG+OmvUliLpDYBuaT3zfHm9RUVWMD8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00054

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}