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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c3b0f4e8d23fc0c13dec461c1e3d757efc1174217e0ac419e0dd05de9772f2c9' 
  AND token = 'fUDJ92Uz4NAGA6PwHi0PZmsv203cMdL3X50gQYrc5Jg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}