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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7d6203f7b108864d02b40daeea024913d4a9a707dec2c6d928d5148f56feb4b2' 
  AND token = 'g5rHi5lV+vygDlDbQ75+ZaxCHS59//V6JIlY3gl0Dlg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}