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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '04c52fdcf09b4a0f837d47d4b44385cc528f79dfd6ccd67ac70505c7dd15bf00' 
  AND token = 'a56wF5UTuQQD8fl4j+eKgjEl9C449Fk2lThSIWP13qU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}