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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6e149c6d121d6ea21081f1f55ad764edc2cf7b980474ce39aa8f5cd57bdc7662' 
  AND token = 'eAh+oAQDOw/ZVka1JJ2PCEafvh2KZrxOLCjiwIwed+g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}