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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '859c85cc854c9a96440c825500408a21c379504d7d93460c5392cd52bd2e3334' 
  AND token = 'mxkM6xV3S/P+BCpwuKpPaVCm/bVSn8f+HEo+Kpjqfcw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}