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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '60572455e0d497c3119a32a90e12c6e204bb54b047d8138b67e0538f3a5cb978' 
  AND token = 'CiF91Rwdaak1Dtg3gAnmxq3KZNlTis1lOI8U3bGBsZs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}