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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fdffdd61eb8475a5391056132bb882315198311a900e25208df25b25b8a6ce1e' 
  AND token = 'mP5QdNF1tv2WqRp0QzAK974rA+c3YYX85NThZ2hR5js=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}