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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '457deb0794a23599143e5cf4b5a34570e488ecd93120f4a7f1fabcf2997a2b72' 
  AND token = 'vgOAW9Xhix9oXol9jaQbxgkOjIMq8CB4hz4u1dg/yFU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}