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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0d0d3b00310768a0d34386dbdf2668a58559c1ae179ad5906a8e8845c1b6956c' 
  AND token = 'MSTWt0NWHaLG2QOeKA8dL4EqfDKQ7gI0l+cjKTJOASI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}