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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0042680dc89ef5472d7b1682a5cc4f1b9994dec13a231830bcc7573bbe653a11' 
  AND token = '8c1ptH/0NKAMMtdT8KCT7brjwE6G4D6CThHDRLqheu4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}