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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '486f4aff012ec7313adbcb25b93e96e808939a3b6655adbadf2631e879539344' 
  AND token = '3LFdQZg9y6gC1F++R99a78w5udppLDRhE/4vuh6PYKU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}