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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b0991cc778c56d8a21aaddbfef553e016b05feb31570c6760ae7c5a46e13de5f' 
  AND token = 'tO6/I7uwcbZiY3sraCXy4YgfBLRj5L1N+x4eCLsxjlE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}