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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4a99c8c26bc4ff63e1c9b9941a4a3c16a49e757c2794d00571fae6c1897edcd2' 
  AND token = '7qJbAZ6MlMZaGG8yjtOp36lvrYlvHjkMLH+oLGYeLmI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}