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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '92d1df421045bcb8cdbe05d121ce05531b9dd81b1f5c00bb35d75a5c205418b0' 
  AND token = 'HfZTL8Ja9ixhxDJ3F10Zv37R9fjAyHGxM4efbuHYg9I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}